MDA-MB-435E人无色素性黑色素瘤癌细胞株BioVector NTCC细胞保藏中心

[Designation名称] NTCC® MDA-MB-435E Cell Line细胞株
BioVector NTCC典型培养物保藏中心

References identifiers: PubMed=10545506;
Comments: Problematic cell line: Contaminated. Parent cell line (MDA-MB-435) has been shown to be a M14 derivative.
Comments: Population: Caucasian.
Comments: Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line).
Comments: Sequence variation: Mutation; HGNC; HGNC:1787; CDKN2A; Simple; c.150+2T>C (IVS1+2T>C); ClinVar=VCV000406712; Zygosity=Heterozygous; Note=Splice donor mutation (from parent cell line).
Comments: Sequence variation: Mutation; HGNC; HGNC:1787; CDKN2A; Simple; c.455insCdel26; Zygosity=Heterozygous (from parent cell line).
Comments: Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly266Glu (c.797G>A); ClinVar=VCV000161516; Zygosity=Heterozygous (from parent cell line).
Comments: Genetic integration: Method=Transfection; Gene=HGNC; HGNC:1748; CDH1.
Comments: Genetic integration: Method=Transfection; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Comments: Derived from site: Metastatic; Right buttock, hypodermis; UBERON=UBERON_0013691+UBERON_0002072.
Diseases: C3802; Amelanotic melanoma
Species of origin: NCBI_TaxID=9606; ! Homo sapiens (Human)
[Organism物种来源]
[Disease疾病种类]
[编号]Accession Number: NTCC® CVCL_F0XN
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[Reference参考文献]
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培养方法：
Medium培养基：NTCC® MDA-MB-435E Complete Medium
Growth properties形态：贴壁/悬浮：
Culture Condition培养条件：Temperature温度: 37°C.
Atmosphere: 95% Air, 5% CO2

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