GIST-882人胃肠道间质瘤 (GIST) 细胞系NTCC® BioVector NTCC保藏中心
- 价 格：¥99850
- 货 号：BioVector®-GIST-882
- 产 地：北京
- BioVector NTCC典型培养物保藏中心
- 联系人：Dr.Xu, Biovector NTCC Inc.
电话：400-800-2947 工作微信:1843439339 (QQ同号)
邮件：Biovector@163.com
手机：18901268599
地址：北京
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BioVector® NTCC® GIST-882人胃肠道间质瘤 (GIST) 细胞系NTCC®
The NTCC® GIST-882 cell line is an adherent human gastrointestinal stromal tumor (GIST) cell line derived from the metastatic liver lesion of a 66-year-old male patient. It is a vital model for GIST research because it carries a specific, activating point mutation in the KIT gene, making it highly sensitive to the drug imatinib (Gleevec). GIST-882 Cell Line Datasheet Characteristic English 中文 (Chinese) Organism Homo sapiens (Human) Homo sapiens (人) Tissue Liver metastasis (Primary site: jejunum) 肝转移灶 (原发部位: 空肠) Disease Gastrointestinal Stromal Tumor (GIST) 胃肠道间质瘤 (GIST) Sex Male 男性 Age 66 years 66 岁 Morphology Spindle-shaped/epithelial-like adherent cells 纺锤形/上皮样贴壁细胞 Growth Properties Adherent monolayer 贴壁单层生长 Doubling Time Approximately 40 hours 约 40 小时 Key Mutation KIT exon 13 point mutation (K642E) KIT 外显子 13 点突变 (K642E) Immunomarker Strongly positive for c-kit (CD117) and CD34 c-kit (CD117) 和 CD34 免疫强阳性 Biosafety Level 1 or 2 (Generally) 1 或 2 级 (通常) Culture Conditions (培养条件) Medium: Dulbecco's Modified Eagle's Medium (DMEM) or RPMI 1640 medium, supplemented with 10% Fetal Bovine Serum (FBS) and antibiotics (e.g., penicillin/streptomycin). Temperature: 37°C CO₂: 5% CO₂ in a humidified incubator. Subculture: Subculture when 70-80% confluent, using trypsin/EDTA solution. 中文资料 (Chinese Datasheet) NTCC® GIST-882 细胞系是一种贴壁人胃肠道间质瘤 (GIST) 细胞系，源自一名 66 岁男性患者的肝转移病灶。它是 GIST 研究的重要模型，因为它携带 KIT 基因的特定激活点突变，使得该细胞系对伊马替尼 (Gleevec) 药物高度敏感。 GIST-882 细胞系参数 特性 English 中文 (Chinese) 生物体 Homo sapiens (Human) Homo sapiens (人) 组织 Liver metastasis (Primary site: jejunum) 肝转移灶 (原发部位: 空肠) 疾病 Gastrointestinal Stromal Tumor (GIST) 胃肠道间质瘤 (GIST) 性别 Male 男性 年龄 66 years 66 岁 形态 Spindle-shaped/epithelial-like adherent cells 纺锤形/上皮样贴壁细胞 生长特性 Adherent monolayer 贴壁单层生长 倍增时间 Approximately 40 hours 约 40 小时 关键突变 KIT exon 13 point mutation (K642E) KIT 外显子 13 点突变 (K642E) 免疫标记 Strongly positive for c-kit (CD117) and CD34 c-kit (CD117) 和 CD34 免疫强阳性 生物安全级别 1 or 2 (Generally) 1 或 2 级 (通常) BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心 电话:400-800-2947 工作QQ/微信同号:1843439339 网址 www.biovector.net
Supplier来源:BioVector NTCC Inc.
Email: biovector@163.com
Website网址: http://www.biovector.net
The NTCC® GIST-882 cell line is an adherent human gastrointestinal stromal tumor (GIST) cell line derived from the metastatic liver lesion of a 66-year-old male patient. It is a vital model for GIST research because it carries a specific, activating point mutation in the KIT gene, making it highly sensitive to the drug imatinib (Gleevec). GIST-882 Cell Line Datasheet Characteristic English 中文 (Chinese) Organism Homo sapiens (Human) Homo sapiens (人) Tissue Liver metastasis (Primary site: jejunum) 肝转移灶 (原发部位: 空肠) Disease Gastrointestinal Stromal Tumor (GIST) 胃肠道间质瘤 (GIST) Sex Male 男性 Age 66 years 66 岁 Morphology Spindle-shaped/epithelial-like adherent cells 纺锤形/上皮样贴壁细胞 Growth Properties Adherent monolayer 贴壁单层生长 Doubling Time Approximately 40 hours 约 40 小时 Key Mutation KIT exon 13 point mutation (K642E) KIT 外显子 13 点突变 (K642E) Immunomarker Strongly positive for c-kit (CD117) and CD34 c-kit (CD117) 和 CD34 免疫强阳性 Biosafety Level 1 or 2 (Generally) 1 或 2 级 (通常) Culture Conditions (培养条件) Medium: Dulbecco's Modified Eagle's Medium (DMEM) or RPMI 1640 medium, supplemented with 10% Fetal Bovine Serum (FBS) and antibiotics (e.g., penicillin/streptomycin). Temperature: 37°C CO₂: 5% CO₂ in a humidified incubator. Subculture: Subculture when 70-80% confluent, using trypsin/EDTA solution. 中文资料 (Chinese Datasheet) NTCC® GIST-882 细胞系是一种贴壁人胃肠道间质瘤 (GIST) 细胞系，源自一名 66 岁男性患者的肝转移病灶。它是 GIST 研究的重要模型，因为它携带 KIT 基因的特定激活点突变，使得该细胞系对伊马替尼 (Gleevec) 药物高度敏感。 GIST-882 细胞系参数 特性 English 中文 (Chinese) 生物体 Homo sapiens (Human) Homo sapiens (人) 组织 Liver metastasis (Primary site: jejunum) 肝转移灶 (原发部位: 空肠) 疾病 Gastrointestinal Stromal Tumor (GIST) 胃肠道间质瘤 (GIST) 性别 Male 男性 年龄 66 years 66 岁 形态 Spindle-shaped/epithelial-like adherent cells 纺锤形/上皮样贴壁细胞 生长特性 Adherent monolayer 贴壁单层生长 倍增时间 Approximately 40 hours 约 40 小时 关键突变 KIT exon 13 point mutation (K642E) KIT 外显子 13 点突变 (K642E) 免疫标记 Strongly positive for c-kit (CD117) and CD34 c-kit (CD117) 和 CD34 免疫强阳性 生物安全级别 1 or 2 (Generally) 1 或 2 级 (通常) BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心 电话:400-800-2947 工作QQ/微信同号:1843439339 网址 www.biovector.net
Supplier来源:BioVector NTCC Inc.
Email: biovector@163.com
Website网址: http://www.biovector.net
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