GIST-T1 人胃肠道间质瘤 (GIST) 细胞系NTCC® BioVector NTCC保藏中心
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- 货 号：BioVector®-GIST-T1
- 产 地：北京
- BioVector NTCC典型培养物保藏中心
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电话：400-800-2947 工作微信:1843439339 (QQ同号)
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地址：北京
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BioVector® NTCC® GIST-T1 人胃肠道间质瘤 (GIST) 细胞系NTCC®
The NTCC® GIST-T1 cell line is an adherent, human gastrointestinal stromal tumor (GIST) cell line derived from a gastric tumor in a Japanese woman. It is a widely used model for studying GIST pathogenesis and drug resistance mechanisms, particularly concerning imatinib mesylate (IM). GIST-T1 Cell Line Datasheet Characteristic English 中文 (Chinese) Organism Homo sapiens (Human) Homo sapiens (人) Tissue Stomach (Gastrointestinal tract) 胃 (胃肠道) Disease Gastrointestinal Stromal Tumor (GIST) 胃肠道间质瘤 (GIST) Sex Female 女性 Ethnicity Asian (Japanese) 亚洲 (日本) Morphology Elongated, spindle-shaped, epithelial-like adherent cells 细长、纺锤形、上皮样贴壁细胞 Growth Properties Adherent monolayer 贴壁单层生长 Doubling Time Approximately 26.59 hours 约 26.59 小时 Key Mutation KIT exon 11 (V560-Y579Δ5 deletion) KIT 外显子 11 突变 (V560-Y579Δ5 缺失) Immunomarker Strongly immunopositive for c-kit (CD117) and CD34 c-kit (CD117) 和 CD34 免疫强阳性 Biosafety Level 1 (Generally) 1 级 (通常) Culture Conditions Medium: Dulbecco's Modified Eagle's Medium (DMEM) or RPMI 1640 medium, supplemented with 10% to 15% Fetal Bovine Serum (FBS) and antibiotics (e.g., penicillin/streptomycin). Temperature: 37°C CO₂: 5% CO₂ in a humidified incubator Subculture: Cells should be subcultured when they reach 70-90% confluence, using 0.25% trypsin. 中文资料 (Chinese Datasheet) NTCC® GIST-T1 细胞系是一种贴壁人胃肠道间质瘤 (GIST) 细胞系，源自一名日本女性的胃部肿瘤。它是研究 GIST 发病机制和耐药性机制（特别是针对甲磺酸伊马替尼 (IM)）的常用模型。 GIST-T1 细胞系参数 特性 English 中文 (Chinese) 生物体 Homo sapiens (Human) Homo sapiens (人) 组织 Stomach (Gastrointestinal tract) 胃 (胃肠道) 疾病 Gastrointestinal Stromal Tumor (GIST) 胃肠道间质瘤 (GIST) 性别 Female 女性 种族 Asian (Japanese) 亚洲 (日本) 形态 Elongated, spindle-shaped, epithelial-like adherent cells 细长、纺锤形、上皮样贴壁细胞 生长特性 Adherent monolayer 贴壁单层生长 倍增时间 Approximately 26.59 hours 约 26.59 小时 关键突变 KIT exon 11 (V560-Y579Δ5 deletion) KIT 外显子 11 突变 (V560-Y579Δ5 缺失) 免疫标记 Strongly immunopositive for c-kit (CD117) and CD34 c-kit (CD117) 和 CD34 免疫强阳性 生物安全级别 1 (Generally) 1 级 (通常) 培养条件 培养基： 使用补充 10% 至 15% 胎牛血清 (FBS) 和抗生素（如青霉素/链霉素）的 Dulbecco's Modified Eagle's Medium (DMEM) 或 RPMI 1640 培养基。 温度： 37°C CO₂： 在 37°C、5% CO₂ 培养箱中培养。 传代： 当细胞汇合度达到 70-90% 时，使用 0.25% 胰蛋白酶进行传代。 BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心 电话:400-800-2947 工作QQ/微信同号:1843439339 网址 www.biovector.net
Supplier来源:BioVector NTCC Inc.
Email: biovector@163.com
Website网址: http://www.biovector.net
The NTCC® GIST-T1 cell line is an adherent, human gastrointestinal stromal tumor (GIST) cell line derived from a gastric tumor in a Japanese woman. It is a widely used model for studying GIST pathogenesis and drug resistance mechanisms, particularly concerning imatinib mesylate (IM). GIST-T1 Cell Line Datasheet Characteristic English 中文 (Chinese) Organism Homo sapiens (Human) Homo sapiens (人) Tissue Stomach (Gastrointestinal tract) 胃 (胃肠道) Disease Gastrointestinal Stromal Tumor (GIST) 胃肠道间质瘤 (GIST) Sex Female 女性 Ethnicity Asian (Japanese) 亚洲 (日本) Morphology Elongated, spindle-shaped, epithelial-like adherent cells 细长、纺锤形、上皮样贴壁细胞 Growth Properties Adherent monolayer 贴壁单层生长 Doubling Time Approximately 26.59 hours 约 26.59 小时 Key Mutation KIT exon 11 (V560-Y579Δ5 deletion) KIT 外显子 11 突变 (V560-Y579Δ5 缺失) Immunomarker Strongly immunopositive for c-kit (CD117) and CD34 c-kit (CD117) 和 CD34 免疫强阳性 Biosafety Level 1 (Generally) 1 级 (通常) Culture Conditions Medium: Dulbecco's Modified Eagle's Medium (DMEM) or RPMI 1640 medium, supplemented with 10% to 15% Fetal Bovine Serum (FBS) and antibiotics (e.g., penicillin/streptomycin). Temperature: 37°C CO₂: 5% CO₂ in a humidified incubator Subculture: Cells should be subcultured when they reach 70-90% confluence, using 0.25% trypsin. 中文资料 (Chinese Datasheet) NTCC® GIST-T1 细胞系是一种贴壁人胃肠道间质瘤 (GIST) 细胞系，源自一名日本女性的胃部肿瘤。它是研究 GIST 发病机制和耐药性机制（特别是针对甲磺酸伊马替尼 (IM)）的常用模型。 GIST-T1 细胞系参数 特性 English 中文 (Chinese) 生物体 Homo sapiens (Human) Homo sapiens (人) 组织 Stomach (Gastrointestinal tract) 胃 (胃肠道) 疾病 Gastrointestinal Stromal Tumor (GIST) 胃肠道间质瘤 (GIST) 性别 Female 女性 种族 Asian (Japanese) 亚洲 (日本) 形态 Elongated, spindle-shaped, epithelial-like adherent cells 细长、纺锤形、上皮样贴壁细胞 生长特性 Adherent monolayer 贴壁单层生长 倍增时间 Approximately 26.59 hours 约 26.59 小时 关键突变 KIT exon 11 (V560-Y579Δ5 deletion) KIT 外显子 11 突变 (V560-Y579Δ5 缺失) 免疫标记 Strongly immunopositive for c-kit (CD117) and CD34 c-kit (CD117) 和 CD34 免疫强阳性 生物安全级别 1 (Generally) 1 级 (通常) 培养条件 培养基： 使用补充 10% 至 15% 胎牛血清 (FBS) 和抗生素（如青霉素/链霉素）的 Dulbecco's Modified Eagle's Medium (DMEM) 或 RPMI 1640 培养基。 温度： 37°C CO₂： 在 37°C、5% CO₂ 培养箱中培养。 传代： 当细胞汇合度达到 70-90% 时，使用 0.25% 胰蛋白酶进行传代。 BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心 电话:400-800-2947 工作QQ/微信同号:1843439339 网址 www.biovector.net
Supplier来源:BioVector NTCC Inc.
Email: biovector@163.com
Website网址: http://www.biovector.net
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