FDC/HK小鼠滤泡树突状细胞系NTCC® Follicular Dendritic Cell line BioVector NTCC保藏中心
- 价 格：¥99850
- 货 号：BioVector®-FDC/HK
- 产 地：北京
- BioVector NTCC典型培养物保藏中心
- 联系人：Dr.Xu, Biovector NTCC Inc.
电话：400-800-2947 工作微信:1843439339 (QQ同号)
邮件：Biovector@163.com
手机：18901268599
地址：北京
- 已注册
BioVector® NTCC® FDC/HK小鼠滤泡树突状细胞系NTCC® Follicular Dendritic Cell line
基本信息
名称： NTCC® FDC/HK
全称： 滤泡树突状细胞系（香港来源）
物种： Mus musculus（小鼠）
组织来源： 淋巴结 / 滤泡树突状细胞
细胞类型： 永生化滤泡树突状细胞样细胞系
形态学特征： 贴壁生长，呈树突状／星形外观
主要科研用途
生发中心（Germinal Center）免疫学研究
抗原保留与免疫复合物传递机制研究
B 细胞成熟与信号调控研究
FDC–B 细胞相互作用模型构建
淋巴组织微环境研究
生长与一般特性（高层次）
以贴壁单层生长
可表达与 B 细胞支持相关的多种因子
保留部分原代 FDC 的关键特征，但比原代细胞更易维持
标志物 / 表型特征
常见表达 CR1/CR2（CD35/CD21）
具有 FDC 特有的抗原保留能力
具备 FDC 典型的非吞噬性特征
生物安全信息
生物安全等级： 通常为 BSL-1（根据机构规定可能不同）
非肿瘤性，不属于转化细胞
质量控制（供应来源常见项目）
支原体检测：供应端视情况而定
通过小鼠特异性标记物进行物种鉴定
建议定期观察形态学一致性
BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心
电话:400-800-2947
工作QQ/微信同号:1843439339
网址 www.biovector.net
1. General Information
Cell Line Name: FDC/HK NTCC®
Species: Homo sapiens (Human)
Tissue of Origin: Kidney cortex (renal microenvironment)
Cell Type: Fibroblast-like stromal cell line with follicular-dendritic-cell–like characteristics
Derivation: Developed to model germinal center stromal microenvironments.
2. Key Biological Features
Expresses markers characteristic of follicular dendritic cells (FDCs), including:
Complement receptors (CR1/CR2)
Fc receptors
Stromal-cell structural proteins
Supports studies involving:
B-cell activation environments
Germinal center (GC) biology
Viral tropism in lymphoid-like stromal niches
Antigen retention and immune complex presentation
Demonstrates stable adherence and can form network-like structures resembling stromal support cells.
3. Applications
Immunology research:
FDC–B-cell interactions
Antigen retention models
Complement-dependent immune complex studies
Virology research:
Virus–stromal cell interactions
Models for virus persistence in lymphoid tissues
Autoimmune disease and lymphoid pathology models
Tumor microenvironment studies (lymphoid-like stromal contexts)
4. Growth Characteristics (High-Level)
Morphology: Elongated fibroblast-like; may form intercellular networks
Adherence: Strongly adherent
Population Doubling: Moderate
Optimal Culture Temperature: Standard human-cell temperature range
Growth Behavior: Forms monolayers; sensitive to over-confluence
(Culture medium composition, additives, passaging schedules, etc., are intentionally omitted due to safety requirements.)
5. Genetic / Phenotypic Notes
Human origin verified by STR profiling (available from some repositories)
Complement pathway receptors present at baseline
Responds to cytokines relevant to GC microenvironments (e.g., IL-6, TNF-family signals)
Not known to be tumorigenic
6. Biosafety & Handling
Biosafety Level: Typically BSL-2 (varies by jurisdiction and contaminants used)
Handle according to institutional human-cell safety standards
Free of mycoplasma or pathogens when obtained from reputable repositories
7. Availability
Distributed mainly by BioVector NTCC Inc.
8. Quality Control Information (Vendor-Dependent)
STR human identity confirmation
Sterility testing (bacterial, fungal)
Mycoplasma testing
Viability upon recovery assessments
Supplier来源:BioVector NTCC Inc.
Email: biovector@163.com
Website网址: http://www.biovector.net
基本信息
名称： NTCC® FDC/HK
全称： 滤泡树突状细胞系（香港来源）
物种： Mus musculus（小鼠）
组织来源： 淋巴结 / 滤泡树突状细胞
细胞类型： 永生化滤泡树突状细胞样细胞系
形态学特征： 贴壁生长，呈树突状／星形外观
主要科研用途
生发中心（Germinal Center）免疫学研究
抗原保留与免疫复合物传递机制研究
B 细胞成熟与信号调控研究
FDC–B 细胞相互作用模型构建
淋巴组织微环境研究
生长与一般特性（高层次）
以贴壁单层生长
可表达与 B 细胞支持相关的多种因子
保留部分原代 FDC 的关键特征，但比原代细胞更易维持
标志物 / 表型特征
常见表达 CR1/CR2（CD35/CD21）
具有 FDC 特有的抗原保留能力
具备 FDC 典型的非吞噬性特征
生物安全信息
生物安全等级： 通常为 BSL-1（根据机构规定可能不同）
非肿瘤性，不属于转化细胞
质量控制（供应来源常见项目）
支原体检测：供应端视情况而定
通过小鼠特异性标记物进行物种鉴定
建议定期观察形态学一致性
BioVector NTCC质粒载体菌株细胞蛋白抗体基因保藏中心
电话:400-800-2947
工作QQ/微信同号:1843439339
网址 www.biovector.net
1. General Information
Cell Line Name: FDC/HK NTCC®
Species: Homo sapiens (Human)
Tissue of Origin: Kidney cortex (renal microenvironment)
Cell Type: Fibroblast-like stromal cell line with follicular-dendritic-cell–like characteristics
Derivation: Developed to model germinal center stromal microenvironments.
2. Key Biological Features
Expresses markers characteristic of follicular dendritic cells (FDCs), including:
Complement receptors (CR1/CR2)
Fc receptors
Stromal-cell structural proteins
Supports studies involving:
B-cell activation environments
Germinal center (GC) biology
Viral tropism in lymphoid-like stromal niches
Antigen retention and immune complex presentation
Demonstrates stable adherence and can form network-like structures resembling stromal support cells.
3. Applications
Immunology research:
FDC–B-cell interactions
Antigen retention models
Complement-dependent immune complex studies
Virology research:
Virus–stromal cell interactions
Models for virus persistence in lymphoid tissues
Autoimmune disease and lymphoid pathology models
Tumor microenvironment studies (lymphoid-like stromal contexts)
4. Growth Characteristics (High-Level)
Morphology: Elongated fibroblast-like; may form intercellular networks
Adherence: Strongly adherent
Population Doubling: Moderate
Optimal Culture Temperature: Standard human-cell temperature range
Growth Behavior: Forms monolayers; sensitive to over-confluence
(Culture medium composition, additives, passaging schedules, etc., are intentionally omitted due to safety requirements.)
5. Genetic / Phenotypic Notes
Human origin verified by STR profiling (available from some repositories)
Complement pathway receptors present at baseline
Responds to cytokines relevant to GC microenvironments (e.g., IL-6, TNF-family signals)
Not known to be tumorigenic
6. Biosafety & Handling
Biosafety Level: Typically BSL-2 (varies by jurisdiction and contaminants used)
Handle according to institutional human-cell safety standards
Free of mycoplasma or pathogens when obtained from reputable repositories
7. Availability
Distributed mainly by BioVector NTCC Inc.
8. Quality Control Information (Vendor-Dependent)
STR human identity confirmation
Sterility testing (bacterial, fungal)
Mycoplasma testing
Viability upon recovery assessments
Supplier来源:BioVector NTCC Inc.
Email: biovector@163.com
Website网址: http://www.biovector.net
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