PathHunter THP-1 IkappaB Degradation Cancer cell line NTCC®细胞株/完全培养基-BioVector NTCC典型培养物保藏中心
- 价 格：¥98950
- 货 号：NTCC®-KZ70
- 产 地：北京
- BioVector NTCC典型培养物保藏中心
- 联系人：Dr.Xu, Biovector NTCC Inc.
电话：400-800-2947 工作微信:1843439339 (QQ同号)
邮件：Biovector@163.com
手机：18901268599
地址：北京
- 已注册
[Designation名称] NTCC® PathHunter THP-1 IkappaB Degradation Cell Line细胞株
BioVector NTCC Inc.Cross-references: DiscoverX; 93-0538C14Cross-references: Wikidata; Q54938064Cross-references: cancercelllines; NTCC_KZ70Comments: Population: Japanese.Comments: Characteristics: PathHunter degradation cell lines express a target protein tagged with a beta-galactosidase fragment (Enzyme Donor=ED). Pathway activation results in the degradation of the target protein. The degraded protein is detected by adding to the cell lysis buffer another beta-galactosidase fragment (Enzyme Acceptor=EA). Complementation of the ED and EA enzyme fragments result into a catalytically active enzyme that generate a chemiluminescent signal.Comments: Sequence variation: Gene fusion; HGNC; 2457; CSNK2A1 + HGNC; 13917; DDX39B; Name(s)=CSNK2A1-DDX39B (from parent cell line).Comments: Sequence variation: Gene fusion; HGNC; 7132; KMT2A + HGNC; 7136; MLLT3; Name(s)=KMT2A-MLLT3, MLL-MLLT3, MLL-AF9 (from parent cell line).Comments: Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000039648; Zygosity=Heterozygous (from parent cell line).Comments: Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg174fs*3 (c.520_545del26); Zygosity=Heterozygous (from parent cell line).Comments: Transfected with: HGNC; 7797; NFKBIA.Comments: Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.Diseases: NCIt; C9163; Childhood acute monocytic leukemiaDiseases: ORDO; Orphanet_514; Acute monoblastic/monocytic leukemia
[Organism物种来源]
[Disease疾病种类]
[Accession编号] NTCC® Accession: NTCC_KZ70
[Comments描述]
[Reference参考文献]
[Category分类]
[Date保藏时间]
[Synonyms别名]
[Hierarchy]
培养方法：
Medium培养基：NTCC® Specific Complete Medium
Growth properties形态：贴壁/悬浮：
Culture Condition培养条件：Temperature温度: 37°C.Atmosphere: 95% Air, 5% CO2
Supplier生产厂家: BioVector NTCC质粒载体菌种细胞蛋白抗体基因保藏中心
Website网址：www.biovector.net
BioVector NTCC Inc.Cross-references: DiscoverX; 93-0538C14Cross-references: Wikidata; Q54938064Cross-references: cancercelllines; NTCC_KZ70Comments: Population: Japanese.Comments: Characteristics: PathHunter degradation cell lines express a target protein tagged with a beta-galactosidase fragment (Enzyme Donor=ED). Pathway activation results in the degradation of the target protein. The degraded protein is detected by adding to the cell lysis buffer another beta-galactosidase fragment (Enzyme Acceptor=EA). Complementation of the ED and EA enzyme fragments result into a catalytically active enzyme that generate a chemiluminescent signal.Comments: Sequence variation: Gene fusion; HGNC; 2457; CSNK2A1 + HGNC; 13917; DDX39B; Name(s)=CSNK2A1-DDX39B (from parent cell line).Comments: Sequence variation: Gene fusion; HGNC; 7132; KMT2A + HGNC; 7136; MLLT3; Name(s)=KMT2A-MLLT3, MLL-MLLT3, MLL-AF9 (from parent cell line).Comments: Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000039648; Zygosity=Heterozygous (from parent cell line).Comments: Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg174fs*3 (c.520_545del26); Zygosity=Heterozygous (from parent cell line).Comments: Transfected with: HGNC; 7797; NFKBIA.Comments: Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.Diseases: NCIt; C9163; Childhood acute monocytic leukemiaDiseases: ORDO; Orphanet_514; Acute monoblastic/monocytic leukemia
[Organism物种来源]
[Disease疾病种类]
[Accession编号] NTCC® Accession: NTCC_KZ70
[Comments描述]
[Reference参考文献]
[Category分类]
[Date保藏时间]
[Synonyms别名]
[Hierarchy]
培养方法：
Medium培养基：NTCC® Specific Complete Medium
Growth properties形态：贴壁/悬浮：
Culture Condition培养条件：Temperature温度: 37°C.Atmosphere: 95% Air, 5% CO2
Supplier生产厂家: BioVector NTCC质粒载体菌种细胞蛋白抗体基因保藏中心
Website网址：www.biovector.net
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