乳腺癌细胞株和正常细胞株列表Breast cancer and normal cell lines. BioVector NTCC质粒载体菌种细胞基因保藏中心

NTCC® No.

Name

CRL-7227™

Hs 281.T

CRL-7245™

Hs 343.T

CRL-7253™

Hs 362.T

HTB-132™

MDA-MB-468

HTB-27™

MDA-MB-361

CRL-2351™

AU565 [AU-565]

HTB-22™

MCF7

HTB-26™

MDA-MB-231

HTB-128™

MDA-MB-415

HTB-130™

MDA-MB-436

HTB-21™

CAMA-1

HTB-30™

SK-BR-3

Tissue

Cell Type

Disease

mammary gland;

adenocarcinoma

breast

mammary gland;

adenocarcinoma

breast

mammary gland;

adenocarcinoma

breast

mammary gland;

adenocarcinoma

breast

mammary gland;

adenocarcinoma

breast: brain

mammary gland;

breast: malignant

adenocarcinoma

pleural effusion

mammary gland;

breast: pleural

epithelial

adenocarcinoma

effusion

mammary gland;

breast: pleural

epithelial

adenocarcinoma

effusion

mammary gland;

breast: pleural

adenocarcinoma

effusion

mammary gland;

breast: pleural

adenocarcinoma

effusion

mammary gland;

breast: pleural

adenocarcinoma

effusion

mammary gland;

breast: pleural

adenocarcinoma

effusion

Age

Ethnicity

Genes Expressed

37 years

Caucasian

47 years

Caucasian

78 years

Caucasian

51 years

Black

Blood Type AB; HLA Aw23,  Aw30, B27, Bw35, Cw2, Cw4

(patient)

40 years

Caucasian

wnt7h +

43 years

Caucasian,

her2/neu + (overexpressed); her3 +; her4 +;  p53 +

White

69 years

Caucasian

insulin-like growth factor  binding proteins (IGFBP) BP-2;

adult

BP-4; BP-5, Blood Type O; Rh+

51 years

Caucasian

adult

38 years

amelogenin (X  chromosome)(AMELEX), Blood Type O

adult

43 years

Caucasian

tubulin; actin

51 years

Caucasian

Blood type O; Rh +; HLA A10, A11, B12, B18

43 years

Caucasian

Blood Type A; Rh+; HLA A11, Bw22(+/-), B40,  B18

NTCC® No.

Name

CRM-HTB-26™

MDA-MB-231

CRL-2116™

JC

CRL-1666™

13762 MAT B III

CRL-1743™

NMU

CRL-1747™

RBA

CRL-3127™

UACC-1179

CRL-3180™

UACC-2087

CRM-HTB-

MDA-MB-231

26D™

CRL-7222™

Hs 274.T

CRL-7477™

Hs 739.T

CRL-7480™

Hs 741.T

CRL-6602™

SMT/2A LNM

CRL-7486™

Hs 748.T

HTB-125™

Hs 578Bst

HTB-126™

Hs 578T

HTB-19™

BT-20

CRL-7347™

Hs 579.Mg

CRL-1897™

UACC-812

HTB-121™

BT-483

HTB-122™

BT-549

CRL-7345™

Hs 574.T

HTB-20™

BT-474

Oganism

Age

Ethnicity

Homo

51 years

Caucasian

sapiens

adult

Mus

1.5

musculus

years

Rattus

norvegicus

Rattus

50 days

norvegicus

adult

Rattus

50 days

norvegicus

adult

Homo

61 years

sapiens

old

Homo

51 years

sapiens

old

Homo

51 years

Caucasian

sapiens

adult

Homo

66 years

Caucasian

sapiens

Homo

52 years

Asian

sapiens

Homo

47 years

Caucasian

sapiens

Rattus

norvegicus

Homo

48 years

Caucasian

sapiens

Homo

74 years

Caucasian

sapiens

Homo

74 years

Caucasian

sapiens

adult

Homo

74 years

Caucasian

sapiens

Homo

Caucasian

sapiens

Homo

43 years

sapiens

Homo

23 years

Caucasian

sapiens

Homo

72 years

Caucasian

sapiens

Homo

sapiens

Homo

60 years

Caucasian

sapiens

adult

NTCC® No.

Name

CRL-2865™

T47D-KBluc

HTB-133™

T-47D

HTB-23™

MDA-MB-134-VI

HTB-25™

MDA-MB-175-VII

CRL-1504™

ZR-75-30

CRL-3121™

UACC-2648

CRL-10317™

MCF 10A

CRL-10318™

MCF 10F

CRL-10781™

MCF-10-2A

CRL-7329™

Hs 564(E).Mg

CRL-2983™

UACC-3199

CRL-7236™

Hs 319.T

CRL-2988™

UACC-3133

CRL-3166™

UACC-732

CRL-2755™

EMT6

HTB-24™

MDA-MB-157

HTB-131™

MDA-MB-453

Cell Type

Disease

epithelial

ductal carcinoma

epithelial

transfected

ductal carcinoma

with reporter

plasmid

Epithelial

ductal carcinoma

ductal carcinoma

epithelial

ductal carcinoma

epithelial

ductal carcinoma

epithelial-like

ductal carcinoma

epithelial

fibrocystic disease

Epithelial,

fibrocystic disease

Myoepithelial

Epithelial

fibrocystic disease

infiltrating ductal carcinoma

infiltrating ductal  carcinoma of the breast

infiltrating ductal cell carcinoma

epithelial-like

infiltrating lobular carcinoma of breast

inflammatory carcinoma of the breast

epithelial

mammary carcinoma

medulallary carcinoma

metastatic carcinoma

Age

Ethnicity

Genes Expressed

63 years

Caucasian

mucin (apomucin, MUC-1, MUC-2)

adult

54 years

adult

54 years

adult

47 years

Caucasian

Blood Type O; Rh+

adult

56 years

Black

47 years

Black

58 yrs

Caucasian

36 years

Caucasian

36 years

36 years

cytokeratin 19. The cells  are positive for epithelial

cytokeratins and milk fat globule antigen.

53 years

Caucasian

adult

58 years

Caucasian

c-erbB-2 positive

old

42 years

Caucasian

52 years

Caucasian

old

33 years

Caucasian

old

44 years

Black

Blood Type B; Rh-

adult

48 years

Caucasian

NTCC® No.

Name

CRL-7482™

Hs 742.T

Age

Ethnicity

Genes Expressed

glycoprotein hormones, alpha  polypeptide(chorionic

gonadotropin, alpha polypeptide, luteinizing  hormone

alpha) [CGA], chorionic gonadotropin, beta  polypeptide,

glycoprotein hormones, alpha polypeptide

surface antigen [sAg]

glycoprotein hormones, alpha  polypeptide(chorionic

gonadotropin, alpha polypeptide, luteinizing  hormone

alpha) [CGA], chorionic gonadotropin, beta  polypeptide,

glycoprotein hormones, alpha polypeptide

57 years

Caucasian

71 years

Caucasian

Epithelial glycoprotein 2  (EGP2), cytokeratin 19, her2/neu

-, p53 +, The cells are  negative for expression of Her2-neu

43 years

Caucasian,

but positive for expression  of p53., The cells are negative

adult

White

for expression of estrogen receptors (ER -)  according to

depositor and negative for expression of  progesterone

receptors (PR -).

HCC1954 overexpresses  her2/neu and is positive for the

61 years

East

epithelial cell specific marker Epithelial  Glycoprotein 2

adult

Indian

and for cytokeratin 19, and is negative for  expression of

estrogen receptor (ER) and  progesterone receptor (PR).

Epithelial glycoprotein 2 (EGP2), cytokeratin  19, her2/

67 years

neu +, p53 +, The cells are positive for  expressions of

Black

Her2-neu and p53  oncogenes., The cells are negative for

adult

expression of estrogen  receptor (ER) and for expression of

progesterone receptor (PR).

Epithelial glycoprotein 2 [EGP2]; cytokeratin  19, her2/

neu -; p53 +, The cells are negative for  expression of

52 years

Her2-neu but positive for  expression of p53., HCC1143 is

Caucasian

positive for the epithelial cell specific  marker Epithelial

adult

Glycoprotein 2 and for  cytokeratin 19, and is negative for

expression of estrogen receptor (ER) and  progesterone

receptor (PR).

41 years

Caucasian,

Epithelial glycoprotein 2  (EGP2), cytokeratin 19, her2/neu

adult

White

-, p53 +

Epithelial glycoprotein 2  [EGP2]; cytokeratin 19, her2/neu

-, p53 -, The cells are  negative for expression of Her2-neu

60 years

Black

and for expression of p53., The cells are  negative for

expression of estrogen  receptor (ER) and for expression of

progesterone receptor (PR).

Epithelial glycoprotein 2 (EGP2), cytokeratin  19, her2/

neu -, p53 +, The cells are negative for  expression of

32 years

Black

Her2-neu but positive for  expression of p53., The cells are

positive for expression of  estrogen receptor (ER) and for

expression of progesterone receptor (PR).

NTCC® No.

Name

Tissue

Cell Type

mammary gland;

Epithelial

breast/duct

mammary gland;

lymphoblast,

breast/duct

epithelial

mammary gland;

Epithelial

breast/duct

mammary gland;

Epithelial

breast/duct

mammary gland;

Epithelial,

breast/duct

lymphoblast

mammary gland;

Epithelial

breast

mammary gland;

Epithelial,

breast/duct

lymphoblast

mammary gland;

Epithelial

breast/duct

mammary gland;

Epithelial

breast

Oganism

Age

Homo

50 years

sapiens

adult

Homo

23 years

sapiens

adult

Homo

48 years

sapiens

adult

Homo

82 years

sapiens

Homo

44 years

sapiens

adult

Homo

42 years

sapiens

Homo

38 years

sapiens

adult

Homo

49 years

sapiens

Homo

70

sapiens

Ethnicity

Genes Expressed

The cells are negative for expression of  Her2-neu but

positive for expression of p53, HCC38 is  positive for the

Caucasian,

epithelial cell specific marker Epithelial  Glycoprotein

White

2 [EGP2] and for cytokeratin 19, and is  negative for

expression of estrogen receptor (ER) and  progesterone

receptor (PR).

Epithelial glycoprotein 2  (EGP2), cytokeratin 19, BRCA1

(mutated, insertion C at nucleotide 5382),  her2/neu -,

Caucasian

p53 -, The cells are negative for expression  of Her2-neu

and for expression of p53., The cells are  negative for

expression of estrogen receptor (ER) and  progesterone

receptor (PR)

Epithelial glycoprotein 2  [EGP2]; cytokeratin 19, her2/neu

+, p53 +, The cells are  positive for expression of Her2-neu

Black

and for expression of p53., The cells are  negative for

expression of estrogen receptor (ER -), but  positive for

expression of progesterone receptor (PR +).

Epithelial glycoprotein 2  [EGP2]; cytokeratin 19, her2/neu

Caucasian,

+, p53 -, The cells are  positive for expression of Her2-neu,

but are negative for expression of p53., The  cells are

White

negative for expression of estrogen receptor  (ER -) and

progesterone receptor (PR -).

Epithelial glycoprotein 2  [EGP2]; cytokeratin 19, her2/neu

Caucasian,

-, p53 -, The cells are  negative for expression of Her2-neu

and for expression of p53., The cells are  negative for

White

expression of estrogen  receptor (ER) and for expression of

progesterone receptor (PR).

Epithelial glycoprotein 2 [EGP2]; cytokeratin  19, her2/

neu +, p53 -, The cells overexpress Her2-neu  but are

negative for expression of p53. HCC1419 is  positive for

Hispanic

the epithelial cell specific marker epithelial  glycoprotein

2 (EGP2) and for  cytokeratin 19. The cells are negative for

expression of estrogen  receptor (ER) and for expression of

progesterone receptor (PR).

Epithelial glycoprotein 2 [EGP2]; cytokeratin  19, her2/

Caucasian,

neu +, p53 +, The cells are  highly positive for expression

of Her2/neu, and are also  positive for expression of p53.,

White

The cells are negative for  expression of estrogen receptor

(ER -).

Epithelial glycoprotein 2 [EGP2];  cytokeratin 19, her2/neu

-, p53 + (overexpressed),  The cells overexpress p53, and

Black

are negative for the  expression of Her2-neu oncogenes.,

The depositor of CRL-2315 initially reported  the cells

were positive for estrogen receptors.

Epithelial glycoprotein 2 [EGP2]; cytokeratin  19, her2/

neu +, p53 -, positive for expression of  Her2-neu and

negative for expression of  p53., The cells are negative for

Black

expression of estrogen  receptor (ER) and for expression

of progesterone receptor  (PR) by immunohistochemistry,

but PR expression was detectable at a low  level by

cytosolic protein assay.

NTCC® No.

Name

CRL-10782™

MCF-12A

CRL-10783™

MCF-12F

CRL-2713™

MDA-kb2

CRL-7365™

Hs 605.T

CRL-7940™

SW527 [SW 527,

SW-527]

HTB-123™

DU4475

CRL-8798™

184A1

CRL-8799™

184B5

CRL-7721™

MB 157

CRL-6299™

CMMT

CCL-51™

MMT 060562

CRL-1615™

CL-S1

CRL-1636™

NMuMG

CRL-1804™

C127: LT

CRL-6376™

MM3MG

Cell Type

Disease

Epithelial

TNM stage IV, grade 4, adenocarcinoma

visualization of sarcoma virus-induced foci

and for an in vitro quantitative assay for bo-

vine papilloma virus. Host for transfection

with plasmids containing bovine papilloma

virus DNA., visualization of sarcoma virus-

induced foci and for an in vitro quantitative

assay for bovine papilloma virus. Host for

transfection with plasmids containing bovine

papilloma virus DNA., transfection with plas-

mids containing bovine  papilloma virus DNA.,

s for transformation with bovine papilloma

virus DNA plasmid

Oganism

Age

Ethnicity

Genes Expressed

Homo

49 years

Caucasian,

HCC1428 cells are positive  for the expression of Epithelial

sapiens

White

glycoprotein 2 [EGP2]; cytokeratin 19

epithelial mucin, milk fat globule membrane  antigen,

Homo

60 years

Caucasian

sialomucin, The cells are positive for  epithelial

sapiens

adult

cytokeratins 8, 14 and 18, and negative for  cytokeratin

19.

Homo

60 years

Caucasian

Cells derived from a  floating population are available (see

sapiens

MCF-12F, NTCC CRL-10783).

Homo

48 years

Caucasian

luciferase, androgen receptor

sapiens

adult

Homo

61 years

Caucasian

sapiens

Homo

70 years

Caucasian

blood type A; Rh+

sapiens

Homo

70 years

Caucasian

sapiens

Homo

21 years

sapiens

Homo

21 years

sapiens

Homo

48 years

Black

sapiens

adult

Macaca

adult

mulatta

Mus

musculus

Mus

plasminogen activator (low amounts)

musculus

Mus

musculus

Mus

musculus

Mus

musculus

NTCC® No.

Name

CRL-6378™

MM5MTC

CRL-6468™

+/+ MGT

CRL-2283™

LA7

CRL-6599™

Rn2T

CRL-6230™

CF37.Mg

CRL-6232™

CF41.Mg

CRL-7336™

Hs 566(B).T

CRL-7368™

Hs 606.T

CRL-3063™

Eph4Ev

CRL-3069™

B-MEKDD 116

CRL-3071™

Eph4 1424

CRL-3086™

M158

CRL-3090™

NF639

CRL-3092™

Ac 711

CRL-1637™

Mm5MT

CRL-7242™

Hs 329.T

CRL-7256™

Hs 371.T

CRL-7145™

Hs 190.T

CRL-7246™

Hs 344.T

CRL-7248™

Hs 350.T

CRL-7379™

Hs 617.Mg

CRL-7574™

Hs 841.T

CRL-7583™

Hs 849.T

CRL-7584™

Hs 851.T

Tissue

Cell Type

Disease

mammary gland

mammary gland

mammary gland

Epithelial

mammary gland

mammary gland

mammary gland

mammary gland;

breast

mammary gland;

breast

Mammary

Epithelium

Mammary

Epithelial

Mammary

Mammary

Mammary

Mammary

mammary gland

mammary gland;

breast

mammary gland;

breast

mammary gland;

breast

mammary gland;

breast

mammary gland;

breast

mammary gland;

breast

mammary gland;

breast

mammary gland;

breast

mammary gland;

breast

Age

Ethnicity    Genes Expressed

54 years

Caucasian

28 years

Caucasian

11 years

Caucasian

49 years

Caucasian

55 years

Caucasian

71 years

Caucasian

adult

48 years

41 years

Caucasian

61 years

Caucasian

NTCC® No.

Name

Tissue

Cell Type

Disease

Oganism

Age

Ethnicity

Genes Expressed

CRL-7596™

Hs 861.T

mammary gland;

Homo

42 years

breast

sapiens

CRL-7612™

Hs 875.T

mammary gland;

Homo

21 years

Caucasian

breast

sapiens

CRL-6373™

MM2MT

mammary gland

Mus

musculus

CRL-6449™

RIIIMT

mammary gland

Mus

adult

musculus

CRL-6598™

Rn1T

mammary gland

Rattus

2 years

norvegicus

CRL-6231™

CF38.Mg

mammary gland

Canis

2 years

familiaris

mammary gland;

Canis

CRL-6228™

CF34.Mg

spontaneous

10 years

familiaris

tumor