Human 5-HT6 Serotonin Receptor Cell Line稳转细胞株 BioVector NTCC质粒载体菌种细胞基因保藏中心

Human 5-HT6 Serotonin Receptor Cell Line稳转细胞株

Serotonin (5-hydroxytryptamine, 5-HT) exerts its many physiological effects through 13 distinct receptor subtypes in humans. These subtypes fall into seven structurally-defined classes (5HT1 to 5HT7). 5-HT6 receptor is expressed in several human brain regions, most prominently in the caudate nucleus. It is positively coupled to adenylcyclase and has pharmacological properties with high affinity for several therapeutically important antidepressant and antipsychotic drugs, in particular the atypical antipsychotic clozapine and related compounds.

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