首页 » Human Kv7.2/Kv7.3 Potassium Channel Cell Line稳转细胞株 BioVector NTCC质粒载体菌种细胞基因保藏中心

Human Kv7.2/Kv7.3 Potassium Channel Cell Line稳转细胞株 BioVector NTCC质粒载体菌种细胞基因保藏中心

  • 价  格:¥1989860
  • 货  号:Human Kv7.2/Kv7.3 Potassium Channel Cell Line
  • 产  地:北京
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Human Kv7.2/Kv7.3 Potassium Channel Cell Line稳转细胞株

The human KCNQ2 and KCNQ3 genes encode the pore-forming subunits of Kv7.2 and Kv7.3, respectively. These subunits form heteromeric voltage-gated potassium channels that underlie M-current that regulates repetitive neuronal activity. Mutations in KCNQ2 or KCNQ3 that reduce M-current amplitude are responsible for some forms of benign familial neonatal seizure. Kv7.2/Kv7.3 channels are therapeutic targets in seizure, stroke, migraine, dementia, bipolar disorder, anxiety, and neuropathic pain.

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