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CHO-K1/PD-L2
DescriptionProgrammed cell death 1 ligand 2 (PD-L2) is a protein that in humans is encoded by the PDCD1LG2 gene. PDCD1LG2 has also been designated as CD273 (cluster of differentiation 273). Inhibitory molecules of the B7/CD28 family play a key role in the induction of immune tolerance in the tumor microenvironment. The programmed death-1 receptor (PD-1), with its ligands PD-L1 and PD-L2, constitutes an important member of these inhibitory pathways. PD-L2 expression was initially thought to be restricted to antigen-presenting cells such as macrophages and dendritic cells (DCs). PD-L2 expression can be induced on a wide variety of other immune cells and nonimmune cells depending on microenvironmental stimuli.SynonymsB7DC; Btdc; CD273; PDCD1L2; bA574F11.2Species HumanFreeze Medium 95% complete growth medium, 5% DMSOCulture Medium F12K, 10% FBS, 8 μg/ml PuromycinProperties Stability 15 passagesStorage Liquid nitrogen immediately upon receivingApplications Binding assay or use as immunogen
Supplier来源:BioVector NTCC Inc.
TEL电话:+86-010-53513060
Website网址: http://www.biovector.net
DescriptionProgrammed cell death 1 ligand 2 (PD-L2) is a protein that in humans is encoded by the PDCD1LG2 gene. PDCD1LG2 has also been designated as CD273 (cluster of differentiation 273). Inhibitory molecules of the B7/CD28 family play a key role in the induction of immune tolerance in the tumor microenvironment. The programmed death-1 receptor (PD-1), with its ligands PD-L1 and PD-L2, constitutes an important member of these inhibitory pathways. PD-L2 expression was initially thought to be restricted to antigen-presenting cells such as macrophages and dendritic cells (DCs). PD-L2 expression can be induced on a wide variety of other immune cells and nonimmune cells depending on microenvironmental stimuli.SynonymsB7DC; Btdc; CD273; PDCD1L2; bA574F11.2Species HumanFreeze Medium 95% complete growth medium, 5% DMSOCulture Medium F12K, 10% FBS, 8 μg/ml PuromycinProperties Stability 15 passagesStorage Liquid nitrogen immediately upon receivingApplications Binding assay or use as immunogen
Supplier来源:BioVector NTCC Inc.
TEL电话:+86-010-53513060
Website网址: http://www.biovector.net
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