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RBL-SX38 cell line细胞株
The rat basophilic leukemia RBL-SX38 cell line expresses a functional human high-affinity IgE receptor, FcεRI receptor, with all 3 chains (α, β, and γ). This enables these cells to be passively sensitized with human IgE molecules and subsequently stimulated with agents that crosslink human IgE and lead to mediator secretion.
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