XRN1基因表达质粒pcDNA3.1-Xrn1，敲除质粒pCas9-XRN1 BioVector NTCC质粒载体菌种细胞基因保藏中心

XRN1基因表达质粒pcDNA3.1-Xrn1，敲除质粒pCas9-XRN1

RefSeq NM_019001.1, NM_019001.2, NM_019001.3, NM_019001.4, NP_061874.2, NP_061874.3 RefSeq Size 10123 RefSeq ORF 5121 Locus ID 54464 Cytogenetics 3q23 Protein Pathways RNA degradation MW 193.9 kDa Gene Summary This gene encodes a member of the 5'-3' exonuclease family. The encoded protein may be involved in replication-dependent histone mRNA degradation, and interacts directly with the enhancer of mRNA-decapping protein 4. In addition to mRNA metabolism, a similar protein in yeast has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly. Mutations in this gene are associated with osteosarcoma, suggesting that the encoded protein may also play a role in bone formation. Alternative splicing results in multiple transcript variants

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