OCI-AML-3 BioVector NTCC质粒载体菌种细胞基因保藏中心

OCI-AML-3

Cell line name OCI-AML-3
Synonyms OCI/AML-3; OCI-AML3; OCI/AML3; OCI AML3; OCIAML3; Ontario Cancer Institute-Acute Myeloid Leukemia-3
Accession CVCL_1844
Resource Identification Initiative To cite this cell line use: OCI-AML-3 (RRID:CVCL_1844)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Part of: LL-100 blood cancer cell line panel.
Doubling time: 28 hours (PubMed=25984343); ~35-40 hours (DSMZ).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: Deep quantitative phosphoproteome analysis.
Omics: Deep RNAseq analysis.
Omics: DNA methylation analysis.
Omics: shRNA library screening.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Peripheral blood.
Sequence variations DNMT3A p.Arg882Cys (c.2644C>T) (PubMed=31160637; DSMZ).
Heterozygous for NPM1 p.Trp288Cysfs*12 (c.860_863dupTCTG) (PubMed=16079892).
Genome ancestry Source: PubMed=30894373

Origin % genome
African 0
Native American 1.44
East Asian, North 2.86
East Asian, South 0
South Asian 0.99
European, North 55.94
European, South 38.78
Disease Adult acute myeloid leukemia (NCIt: C9154)
Acute myeloid leukemia (ORDO: Orphanet_519)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 57Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; DSMZ; PubMed=25877200

Markers:
Amelogenin X
CSF1PO 11,12
D3S1358 16
D5S818 11,13
D7S820 9,10
D8S1179 10,12
D13S317 8,13
D16S539 11,13
D18S51 12,18
D21S11 29,30
FGA 22
Penta D 12,13
Penta E 11,13
TH01 8,10
TPOX 8,11
vWA 17,18

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