WM35 cell line细胞株 BioVector NTCC质粒载体菌种细胞基因保藏中心

WM35 cell line细胞株

Cell line name WM35
Synonyms WM-35; WM 35; WC00060
Accession CVCL_0580
Resource Identification Initiative To cite this cell line use: WM35 (RRID:CVCL_0580)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Part of: Wistar Institute melanoma cell line collection.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: Transcriptome analysis.
Caution: The reported STR profile from Wistar of this cell line was changed at one point between February 2016 when we retrieved them and entered them in the Cellosaurus and May 2018. The major changes were: D18S51: 20->14,15 and FGA: 19->19,24.
Sequence variations Heterozygous for BRAF p.Val600Glu (c.1799T>A) (PubMed=18632627; Wistar).
Genome ancestry Source: PubMed=30894373

Origin % genome
African 0
Native American 0
East Asian, North 0.26
East Asian, South 0.38
South Asian 0.25
European, North 72.7
European, South 26.42
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_A806 (WM35-P1N1) CVCL_A807 (WM35-P1N2) CVCL_A808 (WM35-P1N3)
CVCL_A809 (WM35-P2N1) CVCL_A810 (WM35-P2N2) CVCL_A811 (WM35-P2N3)
Sex of cell Female
Age at sampling 24Y
Category Cancer cell line
STR profile Source(s): ATCC; Cosmic-CLP; PubMed=27087056; Wistar

Markers:
Amelogenin X
CSF1PO 10
D2S1338 18,25
D3S1358 16,18
D5S818 11,12
D7S820 10,13
D8S1179 11,13
D13S317 11
D16S539 12,13
D18S51 14,15
D19S433 15,16
D21S11 29,32.2
FGA 19,24
TH01 9.3
TPOX 8
vWA 17

Run an STR similarity search on this cell line
Web pages https://web.archive.org/web/20141129125241/http://www.wistar.org:80/lab/meenhard-herlyn-dvm-dsc/page/melanoma-cell-lines-0
Publications

PubMed=2253310; DOI=10.1007/BF00046337
Herlyn M.
Human melanoma: development and progression.
Cancer Metastasis Rev. 9:101-112(1990)

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