SK-MEL-5(人恶性黑色素瘤细胞) cell line细胞株 BioVector NTCC质粒载体菌种细胞基因保藏中心

SK-MEL-5(人恶性黑色素瘤细胞) cell line细胞株 BioVector NTCC质粒载体菌种细胞基因保藏中心

Organism: Homo sapiens, human
Tissue: skin: derived from metastatic axillary node.
Disease: malignant melanoma
Cell Type: Melanoma
Age: 24 years
Gender: female
Morphology: stellate
Growth Properties: adherent
Isoenzymes:
AK1,
1
ESD,
1
G6PD, B
GLOI,
12
PGM1, 12
PGM3, 1
DNA Profile:
Amelogenin: X
CSF1PO: 10,13
D13S317: 10,12
D16S539: 10,12
D5S818: 11,13
D7S820: 9,12
THO1: 6,9
TPOX: 11
vWA: 14,18
Cytogenetic Analysis: modal number = 120; range = 95 to 133.
This is a hyperpentaploid human cell line with the modal chromosome number of 120, occurring in 9% of cells.
The majority of cells had chromosome counts of 114123.
Among 14 marker chromosomes that were common
to most cells, generally 9q+ had four copies per cell, t(1q8q) and del(5) (q34) had three copies per cell, and
14q+ had two copies per cell. Numerous others were also found in single copies, all infrequently. Three
normal X chromosomes were found in most cells, N9 was absent, and N7 and N20 had seven to eight copies
per cell.

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