SKW-3 cell line细胞株 BioVector NTCC质粒载体菌种细胞基因保藏中心

SKW-3 cell line细胞株 BioVector NTCC质粒载体菌种细胞基因保藏中心

Cell line name SKW-3
Synonyms SKW3
Accession CVCL_2197
Resource Identification Initiative To cite this cell line use: SKW-3 (RRID:CVCL_2197)
Comments Problematic cell line: Contaminated. Shown to be a KE-37 derivative (PubMed=20143388). Originally thought to originate from the peripheral blood of a 61 year old male patient with T cell chronic lymphocytic leukemia.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00346.
Doubling time: ~30-40 hours (DSMZ); ~30 hours (CLS).
Sequence variations Heterozygous for NOTCH1 p.Gln2459Ter (c.7375C>T) (PubMed=15472075).
Disease Adult T acute lymphoblastic leukemia (NCIt: C9142)
Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1327 (KE-37)
Children:
CVCL_J125 (SK-beta2.7) CVCL_4V58 (SKW3/Clo)
Sex of cell Male
Age at sampling 27Y
Category Cancer cell line
STR profile Source(s): CLS; DSMZ; RCB; TKG

Markers:
Amelogenin X,Y
CSF1PO 10,12
D1S1656 15.3,16
D2S1338 19,25
D3S1358 15,18
D5S818 12,13
D6S1043 18,21
D7S820 8,12
D8S1179 11,14
D12S391 19,22
D13S317 8,12
D16S539 11,12
D18S51 13,18
D19S433 13,15
D21S11 28,29,30
FGA 24,25
Penta D 11,15
Penta E 5,14
TH01 6,9.3
TPOX 8
vWA 17,18

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