TRPV1基因表达质粒敲除载体基因编辑质粒 BioVector NTCC质粒载体菌种细胞基因保藏中心

TRPV1基因表达质粒敲除载体基因编辑质粒 BioVector NTCC质粒载体菌种细胞基因保藏中心

RefSeq: NM_080704.2, NP_542435
RefSeq Size: 4163 RefSeq ORF: 2520
Synonyms : VR1; VR1
LocusID: 7442 Cytogenetic: 17p13.2
Summary: Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene

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