Salmonella typhimurium (strain ATCC 68169 / UK-1) strain菌株菌种 BioVector NTCC质粒载体菌种细胞基因保藏中心

Salmonella typhimurium (strain ATCC 68169 / UK-1) strain菌株菌种 BioVector NTCC质粒载体菌种细胞基因保藏中心
S.typhimurium is a leading cause of human gastroenteritis and is used as a mouse model of human typhoid fever. The incidence of non-typhoid salmonellosis is increasing worldwide, causing millions of infections and many deaths in the human populations each year.

S. typhimurium strain UK-1, where UK stands for universal killer, was isolated from the spleen of a chick orally inoculated 3 days earlier with a highly virulent S. typhimurium strain retrieved from an infected horse in 1991. UK-1 is not only highly invasive and virulent for chickens and mice, but it is also capable of lethal infections in calves, pigs, and horses. Attenuated strains of UK-1 have been used to develop recombinant vaccines in mice (adapted from PMID 21622747).
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