hrgec cell line细胞株细胞系 BioVector NTCC质粒载体菌种细胞基因保藏中心

hrgec cell line细胞株细胞系 BioVector NTCC质粒载体菌种细胞基因保藏中心
Renal glomerular endothelial cells (GEC) are a specialized microvascular cell type involved in the
regulation of glomerular ultrafiltration. They form the inner part of the filtration barrier and are
involved in pathophysiological processes in the glomerulum [1]. GEC constitutively produce bioactive
molecules, which can be amplified by inflammatory and thrombotic molecules [2]. Endothelial
cell injury due to a severe glomerular lesion can inhibit angiogenesis and result in sclerosis at the
injured site [3,4]. GEC injury affects mesangial and epithelial cells and leads to the progression of
renal disease [4]. The biological properties of GEC remain largely unknown because of difficulties
associated with the culturing, cloning and propagation of these cells.
HRGEC from ScienCell Research Laboratories are isolated from human kidneys. HRGEC are
cryopreserved at passage one and delivered frozen. Each vial contains >5 x 105 cells in 1 ml volume.
HRGEC are characterized by immunofluorescence with antibodies specific to vWF/Factor VIII and
CD31 (PECAM). HRGEC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi.
HRGEC are guaranteed to expand beyond 10 population doublings under the conditions specified by
ScienCell Research Laboratories.
Recommended Medium
It is recommended to use Endothelial Cell Medium (ECM, Cat. #1001) for the culturing of HRGEC in
vitro.
【Supplier来源】BioVector NTCC Inc.
TEL：+86-010-53513060
【Website网址】 http://www.biovector.net