pcDNA3.1/FDH基因表达质粒载体 BioVector NTCC质粒载体菌种细胞基因保藏中心
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pcDNA3.1/FDH基因表达质粒载体 BioVector NTCC质粒载体菌种细胞基因保藏中心
RefSeq: NM_000671.3, NP_000662
RefSeq Size: 2644 RefSeq ORF: 1125
Synonyms : ADH-3; ADHX; FALDH; FDH; GSH-FDH; GSNOR; HEL-S-60p
LocusID: 128 Cytogenetic: 4q23 Domains: ADH_zinc_N
Summary: This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene.
【Supplier来源】BioVector NTCC Inc.
TEL：+86-010-53513060
【Website网址】 http://www.biovector.net
RefSeq: NM_000671.3, NP_000662
RefSeq Size: 2644 RefSeq ORF: 1125
Synonyms : ADH-3; ADHX; FALDH; FDH; GSH-FDH; GSNOR; HEL-S-60p
LocusID: 128 Cytogenetic: 4q23 Domains: ADH_zinc_N
Summary: This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene.
【Supplier来源】BioVector NTCC Inc.
TEL：+86-010-53513060
【Website网址】 http://www.biovector.net
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