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OX40抗原表达质粒 BioVector NTCC质粒载体菌种细胞基因保藏中心

  • 价  格:¥39865
  • 货  号:OX40抗原表达质粒
  • 产  地:北京
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OX40抗原表达质粒 BioVector NTCC质粒载体菌种细胞基因保藏中心
Human tumor necrosis factor receptor superfamily, member 4 (TNFRSF4)
RefSeq: NM_003327.2, NP_003318
RefSeq Size: 1084 RefSeq ORF: 834
Synonyms : ACT35; CD134; IMD16; OX40; TXGP1L
LocusID: 7293 Cytogenetic: 1p36.33 Domains: TNFR
Summary: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008]
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