H3255GR cell line细胞株细胞系 BioVector NTCC质粒载体菌种细胞基因保藏中心

H3255GR cell line细胞株细胞系 BioVector NTCC质粒载体菌种细胞基因保藏中心
Cell line name NCI-H3255GR Synonyms H3255GR; H3255 GR Comments Selected for resistance to: ChEBI; CHEBI:49668; Gefitinib (ZD1839; Iressa). Disease Lung adenocarcinoma (NCIt: C3512) Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606) Hierarchy Parent: CVCL_6831 (NCI-H3255) Children: CVCL_DI56 (NCI-H3255DR) Sex of cell Female Age at sampling Age unspecified Category Cancer cell line
Publications PubMed=16906227; DOI=10.1172/JCI28656 Engelman J.A., Mukohara T., Zejnullahu K., Lifshits E., Borras A.M., Gale C.M., Naumov G.N., Yeap B.Y., Jarrell E., Sun J., Tracy S., Zhao X., Heymach J.V., Johnson B.E., Cantley L.C., Janne P.A. Allelic dilution obscures detection of a biologically significant resistance mutation in EGFR-amplified lung cancer. J. Clin. Invest. 116:2695-2706(2006)
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