pT3-Nras表达质粒载体 BioVector NTCC质粒载体菌种细胞基因保藏中心

pT3-Nras表达质粒载体 BioVector NTCC质粒载体菌种细胞基因保藏中心
Human neuroblastoma RAS viral (v-ras) oncogene homolog (NRAS)

RefSeq: NM_002524.2, NP_002515
RefSeq Size: 1963 RefSeq ORF: 570
Synonyms : ALPS4; CMNS; N-ras; NCMS; NRAS1; NS6
LocusID: 4893 Cytogenetic: 1p13.2 Domains: ras, RAS, RHO, RAB
Summary: This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.
【Supplier来源】BioVector NTCC Inc.
TEL：+86-010-53513060
【Website网址】 http://www.biovector.net