MultiDrug-resistant Escherichia coli 1093925 strain菌株菌种 BioVector NTCC质粒载体菌种细胞基因保藏中心

MultiDrug-resistant Escherichia coli 1093925 strain菌株菌种 BioVector NTCC质粒载体菌种细胞基因保藏中心
Reports Upon your purchase of this product, you will receive a report containing MIC values, a susceptibility profile, and the DNA sequence information for predicted annotated antibiotic resistance genes and 16S rRNA genes. This report will be provided in multiple formats (.pdf, .txt, .xls, .zip).
Deposited As Escherichia coli
Classification Enterobacteriaceae, Escherichia
Strain Designations 1093925
Application Drug discovery and development
Development of molecular-based detection assays
Development of updated sterility protocols
Isolation Abscess
Isolation Date 2014
Geographic Source Argentina
Biosafety Level 2
Annotated Genes AAC(3)-IIa
AAC(6')-Ib-cr
acrA
acrB
acrD
acrE
acrF
baeR
CMY-47
CTX-M-15
emrB
emrE
KPC-2
macA
macB
marA
mdtB
mdtC
mdtF
msbA
OXA-1
tet(A)
tolC
Type Strain no
MIC Range Susceptible
Amikacin: ≤16 µg/mL
Fosfomycin: ≤64 µg/mL
Trimethoprim-sulfamethoxazole: ≤2/38 µg/mL


Resistant
Amoxicillin-clavulanate: ≥32/16 µg/mL
Aztreonam: ≥16 µg/mL
Cefepime: ≥16 µg/mL
Ceftazidime: ≥16 µg/mL
Ceftriaxone: ≥4 µg/mL
Ciprofloxacin: ≥4 µg/mL
Doripenem: ≥4 µg/mL
Imipenem: ≥4 µg/mL
Levofloxacin: ≥8 µg/mL
Meropenem: ≥4 µg/mL
Piperacillin-tazobactam: ≥128/4 µg/mL
Tetracycline: ≥16 µg/mL


Comments This strain is part of the Global Priority Superbugs collection. It is an extensively characterized antimicrobial-resistant clinical isolate with validated genotypic and phenotypic activity against a variety of drug classes. This strain is provided with geographic source information; an NGS-assembled whole genome sequence, including annotated antibiotic resistance and rRNA genes; and an expanded level of susceptibility data with MIC test results.

Minimum inhibitory concentration (MIC) ranges for resistant, intermediate, and susceptible are based on criteria within the Clinical and Laboratory Standards Institute (CLSI) Performance Standards for Antimicrobial Susceptibility Testing, 26th Edition.

Predicted antimicrobial resistance gene sequence data are provided for informational purposes only and are based on open reading frames (ORFs) identified and annotated from contigs produced during NextGen Sequencing (NGS). ATCC does not warrant that the entire predicted antimicrobial resistance gene is present within the sequence prepared for lot-specific reports. Likewise, the information provided merely indicates that some portion of the sequence (whole or in part) is present based on analytical base pair alignment with known gene sequences.
Medium Trypticase Soy Agar/Broth
Growth Conditions Temperature: 37°C
Atmosphere: Aerobic
Isolation Abscess
Isolation Date 2014
Geographic Source Argentina
Patient Age 50
Patient Gender Male
References Clinical and Laboratory Standards Institute (CLSI). Performance Standards for Antimicrobial Susceptibility Testing, 26th Edition. Wayne, PA. M100S, 2016.

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