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Puc19-hGCLC BioVector NTCC质粒载体菌种细胞基因保藏中心

  • 价  格:¥19865
  • 货  号:Puc19-hGCLC
  • 产  地:北京
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BioVector NTCC典型培养物保藏中心
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Puc19-hGCLC BioVector NTCC质粒载体菌种细胞基因保藏中心
Reference Data
RefSeq: NM_001197115.1, NP_001184044
RefSeq Size: RefSeq ORF: 1800
Synonyms : GCL; GCS; GLCL; GLCLC
LocusID: 2729 Cytogenetic: 6p12.1
Summary: Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.[provided by RefSeq, Oct 2
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