pCMV-TTF1-myc-Flag BioVector NTCC质粒载体菌种细胞基因保藏中心

pCMV-TTF1-myc-Flag BioVector NTCC质粒载体菌种细胞基因保藏中心

RefSeq: NM_007344.2, NP_031370
RefSeq Size: 3137 RefSeq ORF: 2718
Human transcription termination factor, RNA polymerase I (TTF1)
Synonyms : TTF-1; TTF-I
LocusID: 7270 Cytogenetic: 9q34.13
Summary: This gene encodes a transcription termination factor that is localized to the nucleolus and plays a critical role in ribosomal gene transcription. The encoded protein mediates the termination of RNA polymerase I transcription by binding to Sal box terminator elements downstream of pre-rRNA coding regions. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. This gene shares the symbol/alias 'TFF1' with another gene, NK2 homeobox 1, also known as thyroid transcription factor 1, which plays a role in the regulation of thyroid-specific gene expression. [provided by RefSeq, Apr 2011].
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