KM12-C cell line细胞株KCLB 80015 BioVector NTCC质粒载体菌种细胞基因保藏中心

KM12-C cell line细胞株KCLB 80015 BioVector NTCC质粒载体菌种细胞基因保藏中心 KM12-C cell line
Cat No.: KCLB 80015

Cell line name KM12-C
Synonyms KM12 C; KM-12C; KM12C; Km12C
Comments Registration: Chiron Master Culture Collection; CMCC 11611 (CMCC #11611).
Microsatellite instability: Instable (MSI) (PubMed=25926053).
Sequence variation: Heterozygous for APC p.Asn1819fs*7 (from parent cell line).
Sequence variation: Heterozygous for BRCA2 p.Asn1784fs*7 (from parent cell line).
Sequence variation: Heterozygous for PTEN p.Gly129Ter and p.Lys267fs*9 (from parent cell line).
Sequence variation: Heterozygous for TP53 p.Arg72fs*51 (from parent cell line).
Omics: miRNA expression profiling.
Omics: Transcriptome analysis.
Disease Colon carcinoma (NCIt: C4910)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1331 (KM12)
Category Cancer cell line

Publications
PubMed=2846163
Morikawa K., Walker S.M., Nakajima M., Pathak S., Jessup J.M., Fidler I.J.
Influence of organ environment on the growth, selection, and metastasis of human colon carcinoma cells in nude mice.
Cancer Res. 48:6863-6871(1988)

PubMed=3349467
Morikawa K., Walker S.M., Jessup J.M., Fidler I.J.
In vivo selection of highly metastatic cells from surgical specimens of different primary human colon carcinomas implanted into nude mice.
Cancer Res. 48:1943-1948(1988)

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